NOBLE LIFE SCIENCE PARTNERS (NOBLE LSP) A DIVISION OF NOBLE CAPITAL MARKETS INC. WELCOMES JOSÉE E. LEYSEN, PHD TO ITS SCIENTIFIC ADVISORY BOARD (SAB)

August 2018

Our SAB is a strategic resource whose experience, relationships, and knowledge are utilized throughout NOBLE Life Science Partners to enhance all service offerings. Through the SAB, we have access to world-class healthcare professionals for substantive advice regarding new discoveries, technologies, products, services, and developments.

Josée E. Leysen has worked 36 years as a Scientist, former member of the Research Management Board, and Vice president of Business Development at Janssen Pharmaceutica, Belgium (a Johnson & Johnson company). In 1999 she became a Business Development Executive in Scientific Licensing, where she was responsible for identification and evaluation of licensing and collaboration opportunities in the fields of psychiatry, neurology, and pain at the Johnson & Johnson Pharmaceutical Group. From 1995 to 2011 she was a private professor at the VU University Medical Centre, Amsterdam, The Netherlands and held the title of Professor - Brain Imaging and Receptor Pharmacology at the Department of Nuclear Medicine and PET Research.

Dr. Leysen has published over 230 peer reviewed full research papers, as well as 66 reviews and book chapters. During her career she has been the recipient of several awards including: Johnson Medal for Research & Development (1998); Dr. Paul Janssen Award for Research (1993); Sterling Lecturer at the University of Pennsylvania (1992); and, Lundbeck-Prize for Research in Neuropsychopharmacology and Biological Psychiatry (1989).

Dr. Leysen was amongst the pioneers in receptor research and discovered and characterized the 5-HT2, later classified as 5-HT2A, receptor in the brain and peripheral tissues. Her 5HT2 receptor discovery and research formed the basis for the discovery of risperidone, the prototype of the second generation of so-called ‘atypical’ antipsychotics. She led a team of scientists that contributed to the characterization of several neurotransmitter and neuropeptide receptors and the investigation of the mechanism of action and characterization of drugs that act on the central and peripheral nervous system. She is recognized as an outstanding expert in the field of receptor research and neuropsychopharmacology. Josée E. Leysen obtained maxima cum laude, the degrees of licentiate (Master) in Chemistry in 1968 and Doctor in Science, with specialty in Biochemistry and enzymology in 1972, at the University of Gent Belgium.

About NOBLE Life Science Partners (LSP)
NOBLE Life Science Partners, a division of NOBLE Capital Markets, Inc., established in 1984, is a life science investment and merchant banking boutique built upon fundamental research and scientific due diligence. Through its SAB, healthcare equity research analysts and investment bankers, NOBLE LSP combines industry and scientific knowledge to provide its clients with value-added research, advisory, investment and merchant banking services. The company has offices in Boca Raton (HQ), New York, Boston, and St. Louis. In addition to the annual multi-sector NobleCon, each year Noble hosts numerous "non-deal" corporate road shows and sector-specific conferences.